David Vetter was born without a functioning immune system and spent his life in a bubble that protected him from germs. He died at age 12 in 1984. Scientists are using gene therapy to treat the disorder so that children can live normally.
Researchers say they are achieving success in curing the genetic defect that causes some children to be born without immune defenses, a rare condition made famous in the 1970s by a Texas boy who lived most of his short life in a sterile "bubble."
Scientists now report that 8 out of 9 young children given gene therapy for a type of severe combined immunodeficiency disease, called SCID-X1, are alive and living amid the everyday microbial threats that would otherwise have killed them. The oldest is just over 3 years old.
Fresh Air Weekend highlights some of the best interviews and reviews from past weeks, and new program elements specially paced for weekends. Our weekend show emphasizes interviews with writers, filmmakers, actors, and musicians, and often includes excerpts from live in-studio concerts. This week:
Northern shrimp are shoveled into a holding chamber on a trawler in the Gulf of Maine in 2012. Stocks of the shrimp have been declining for several years, leading regulators to cancel the New England shrimping season.
Credit Tom Porter / Maine Public Broadcasting
Chefs Andrew Taylor, left, and Mike Wiley, co-owners of two Portland, Maine, restaurants, say the moratorium is worth it if it helps sustain the shrimp population.
New England chefs like Andrew Taylor and Mike Wiley are still coming to terms with the news: No more shrimp until further notice.
This week, regulators shut down the New England fishery for Gulf of Maine shrimp for the first time in 35 years. The Atlantic States Marine Fisheries Commission judged the stocks of the popular shrimp, also known as northern shrimp, to be dangerously low.
There's been a string of unsolved murders in Belfast, Northern Ireland, so they have to bring in the heat from London. Detective Superintendent Stella Gibson appears to be the embodiment of what people in Belfast often don't like about London: She seems cool, correct, fiercely intelligent, but icy.
In the latest smog-related health scare in China, officials in Shanghai on Friday ordered schoolchildren to stay indoors, halted all construction and even delayed flights in and out of the city, which has been enveloped in a thick blanket of haze, reducing visibility in places to less than 150 feet.
NPR's Frank Langfitt reports from Shanghai that the commercial capital's Air Quality Index soared above 500 for the first time ever, according to government sensors. He says officials described the readings as "beyond index" — in layman's terms, off-the-charts awful.
Originally published on Fri December 6, 2013 2:20 pm
If you want to eat a more healthful diet, you're going to have to shell out more cash, right? (After all, Whole Foods didn't get the nickname "Whole Paycheck" for nothing.)
But until recently, that widely held bit of conventional wisdom hadn't really been assessed in a rigorous, systematic way, says Dr. Dariush Mozaffarian, a cardiologist and epidemiologist at the Harvard School of Public Health.